Engineered Solutions for Advanced Cell Culture

Bioreactors serve as the core of biological processes, widely used in the production of biopharmaceuticals, vaccines, recombinant proteins, enzymes, and stem cells. Behin Afzar Saz Pooya Co. leverages cutting-edge technology, custom engineering design, and international standards to manufacture and supply a diverse range of bioreactors for research, pilot, and industrial scales.

Classification of Bioreactors

1. Laboratory Bioreactors (Bench-Scale)

• Applications: Ideal for research, product development, and primary cell culture.

• Capacity: Various volumes ranging from 1 to 20 liters.

• Design: Desktop design with precise control over temperature, pH, Dissolved Oxygen (DO), and agitation.

• Interface: Touchscreen HMI with USB/Ethernet connectivity for comprehensive data logging.

• Compatibility: Suitable for adherent, suspension, mammalian, and plant cell cultures.

2. Pilot-Scale Bioreactors

• Capacity: 20 to 500 liters.

• Design: Engineered to meet pilot or semi-industrial production requirements.

• Agitation: Bottom-mounted agitator with magnetic coupling for easy sterilization.

• Automation: Automatic process control system featuring PLC and advanced sensors.

• Integration: Integrated CIP/SIP capability with connectivity to filtration systems.

3. Industrial Bioreactors (Production-Scale)

• Capacity: Large volumes from 500 to 5,000+ liters (Customizable).

• Design: Vertical design with sterilizable engineering for high productivity.

• Applications: Suitable for biopharmaceutical, vaccine, and antibody production lines.

• Structure: Stable performance and robust structure with central monitoring connectivity.

• Features: Multi-stage agitators, efficient heat exchange, and precise aeration control.

4. Single-Use Bioreactors

• Purpose: Suitable for sterile processes requiring disposable components.

• Benefits: Reduces contamination risks and saves significant time on cleaning and validation.

• Usage: Ideal for development phases or rapid, low-volume production.

Common Technical Features

• Material: Constructed from Stainless Steel 316L with sanitary-grade surface finishing.

• Precision Control: Accurate monitoring of critical parameters: temperature, pH, DO, agitation speed, pressure, and aeration.

• Cleaning & Sterility: Equipped with automated CIP/SIP systems for in-place sterilization.

• Smart Interface: Touchscreen HMI connected to PLC/DCS for intelligent process control.

• Connectivity: Capable of integrating with filtration systems, fermenters, media tanks, and auxiliary equipment.

Applications

• Production of recombinant biopharmaceuticals (rDNA).

• Mammalian cell culture for vaccine and antibody manufacturing.

• Microbial, fungal, and plant culture processes.

• Production of enzymes, growth factors, and biological metabolites.

Competitive Advantages

• Custom Engineering: Designs tailored specifically to the customer’s unique biological processes.

• High Precision: Exceptional accuracy in controlling delicate biological environments.

• Flexibility: Modular design for future equipment upgrades or expansion.

• Comprehensive Support: Full technical support, validation, and operator training.

• Regulatory Compliance: Full compliance with GMP, FDA, and CE standards.

Advance your cell culture processes intelligently, safely, and effectively with Behin Afzar Saz Pooya’s advanced bioreactors. Contact us for expert consultation, catalogs, or equipment demonstrations.