Automated, Precise, and Secure In-Place Cleaning & Sterilization

In the pharmaceutical and biotechnology industries, where maintaining cleanliness and sterility and preventing cross-contamination are of vital importance, the use of CIP (Cleaning-in-Place) and SIP (Sterilization-in-Place) skids is an essential solution for ensuring production process safety and quality. Behin Afzar Saz Pooya Company, relying on technical engineering knowledge, designs and manufactures centralized and portable CIP/SIP equipment with automation, customization, and precision control capabilities.

CIP/SIP Skid Functionality

The skids designed by this company allow operators to perform washing and sterilization processes in an automated and controlled manner without dismantling internal systems or equipment. These systems are fully programmable and prevent direct operator contact with chemicals and steam.

Main System Components

• Wash and Water Tanks (PW/WFI): Manufactured from Stainless Steel 316L.

• Sanitary Circulation Pump: Featuring adjustable pressure and flow rates.

• Heat Exchanger or Heating Elements: For regulating washing and sterilization temperatures.

• Automated Valves: Equipped with sanitary actuators for flow direction control.

• Monitoring Sensors: Precise sensors for temperature, pressure, conductivity, and level monitoring.

• Control System: PLC control panel with HMI display for defining and executing process stages.

Types of Available Skids

Centralized CIP/SIP Skid

• Permanent connection to multiple equipment units or production lines.

• Capability to define multiple scenarios and execute various processes simultaneously.

• Suitable for large-scale pharmaceutical or biotech plants.

Portable (Mobile) CIP/SIP Skid

• Compact, portable, and multipurpose design.

• Ideal for pilot lines or equipment requiring periodic cleaning.

• Ease of installation, commissioning, and relocation within sterile environments.

Technical and Functional Advantages

• Increased Efficiency: Boosts production line productivity by reducing downtime and manual cleaning.

• Resource Optimization: Reduces water, energy, and detergent consumption.

• Documentation: Full process validation and documentation capabilities.

• Standard Compliance: Fully compliant with international GMP, FDA, and USP standards.

• Versatility: Ability to define various washing and sterilization programs based on product type and connected equipment.

Applications

• Bioreactors, fermenters, formulation tanks, and storage vessels.

• Sterile drug transfer lines, filtration systems, and media equipment.

• Sterile weighing, filling, and packaging systems.

• In-place cleanable equipment for vaccine, enzyme, biological, and injectable industries.

Transform your production equipment cleaning into a fast, scientific, and secure process with Behin Afzar Saz Pooya’s CIP/SIP skids. Contact us for technical catalogs, expert consultation, or custom design services.